The Reynolds laboratory is dedicated to creating advanced tools to study and combat human diseases, focusing on two main areas:
(1) Controlling HIV. We developed a unique model to precisely set the size of latent simian immunodeficiency virus (SIV) reservoirs in vivo. This model helps us investigate how the size of these reservoirs impacts an individual’s ability to control virus replication after stopping antiretroviral drug treatment.
(2) Antibody wrangling. Our lab has created an efficient method for isolating monoclonal antibodies from memory B cells. We use this method to clone antibodies that can be applied for diagnostic or therapeutic purposes.